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Complement C4c, Human
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| Human C4c produced in Human plasma having a molecular mass of 210kD. It interacts with C1 and C2 to form C3 convertase of the classic activation pathway. Systemic lupus erythematosus (SLE) is often associated with congenital C4 deficiency. Reduced levels of components of the classic pathway (C1, C2, C4, C3) are common after such activation, e.g. in SLE, acute serum sickness and conditions associated with circulating immune complexes | | | Catalog # | C7850-18C | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | Molecular Weight | 210kD | | Source | Human Plasma | | Purity | 99% | | Concentration | As reported | | Form | Supplied as a liquid in sodium phosphate buffer, pH 7.0, 0.15M sodium chloride, 0.09% sodium azide. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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