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You are here:Home » Antibodies » Abs to Complement » Anti -C5, NT (Complement C5, C3 and PZP-like alpha-2-macroglobulin Domain-containing Protein 4, Complement C5 beta Chain, Complement C5 alpha Chain, C5a Anaphylatoxin, Complement C5 alpha' Chain, CPAMD4)

Anti -C5, NT (Complement C5, C3 and PZP-like alpha-2-macroglobulin Domain-containing
Protein 4, Complement C5 beta Chain, Complement C5 alpha Chain, C5a Anaphylatoxin,
Complement C5 alpha' Chain, CPAMD4)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B IH FC
C5 is the fifth component of complement, which plays an important role in inflammatory and cell killing processes. This protein is comprised of alpha and beta polypeptide chains that are linked by a disulfide bridge. An activation peptide, C5a, which is an anaphylatoxin that possesses potent spasmogenic and chemotactic activity, is derived from the alpha polypeptide via cleavage with a convertase. The C5b macromolecular cleavage product can form a complex with the C6 complement component, and this complex is the basis for formation of the membrane attack complex, which includes additional complement components.
Catalog #C7850-24B
ApplicationsSuitable for use in ELISA, Western Blot, Immunohistochemistry and Flow Cytometry. Other applications not tested.
Recommended DilutionsWestern Blot: 1:1000
Immunohistochemistry (FFPE): 1:50-1:100
Flow Cytometry: 1:10-1:50
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs Reported
FormSupplied as a liquid in PBS, 0.09% sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenKLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 253-281 in the N-terminal region of human C5, UniProt Accession #P01031.
SpecificityRecognizes human C5.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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