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You are here:Home » Antibodies » Abs to Complement » Anti -CD88 (C5aR, C5a Receptor 1, C5aR1, Complement Component 5a Receptor 1) (APC)

Anti -CD88 (C5aR, C5a Receptor 1, C5aR1, Complement Component 5a Receptor 1) (APC)

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Specifications

Clone Host Grade Applications
Monoclonal Rat Affinity Purified FC
C5a R1, also known as C5a ligand and CD88, is a 7 transmembrane protein expressed on myeloid, endothelial, epithelial, and smooth muscle cells. C5a R1 binds the activated complement anaphylatoxin C5a. In established allergic environments, this triggers neutrophil and eosinophil chemotaxis and the release of proinflammatory mediators. In contrast, C5a R1/C5a interactions are protective during allergen sensitization. Mouse C5a R1 shares 66-77aa sequence identity with human and rat C5a R, respectively.
Catalog #C7850-24U
ApplicationsSuitable for use in Flow Cytometry. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
HybridomaMyeloma cells with B cells from Balb/c mice.
Absorption 620-650nm
Emission 660-670nm
Storage and StabilityMay be stored at 4°C before opening. DO NOT FREEZE! Stable at 4°C as an undiluted liquid. Dilute only prior to immediate use. Stable for at least 12 months. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer. APC is light sensitive.
Clone TypeMonoclonal
IsotypeIgG2B
Clone No11n36
HostRat
SourceMouse
ConcentrationAs reported
FormSupplied as a liquid in 1ml saline, 0.5% BSA, 0.1% sodium azide. Labeled with Allophycocyanin (APC).
PurityPurified by Protein G affinity chromatography.
ImmunogenRecombinant corresponding to mouse Complement C5a R1 expressed in NSO cells (P30993).
SpecificityRecognizes mouse Complement C5a R1.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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