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You are here:Home » Antibodies » Abs to Complement » Anti -Complement C5, C5b

Anti -Complement C5, C5b

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B
C5 is involved in the activation of the lythic pathway within the complement system which is an important factor in innate immunity. The complement pathways can be divided in the activation pathways and lytic pathway. The activation pathways lead via C3 to the cleavage of the fifth complement component C5 into C5a and C5b. C5b initiates the assembly of the membrane attack complex (MAC) that mediates cytolysis.
Catalog #C7850-25B
ApplicationsSuitable for use in ELISA and Western Blot. Other applications have not been tested.
Recommended DilutionsWestern Blot: 1:10
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG2a
Clone No6A536
HostMouse
SourceHuman
Concentration~0.1mg/ml
FormSupplied as a liquid in PBS, pH 7.4, 0.1% BSA, 0.02% sodium azide.
PurityPurified by Protein G affinity chromatography.
SpecificityRecognizes an epitope on human C5 and on C5b.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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