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Anti -C5b-9 Terminal Complement Complex (TCC)
Anti -C5b-9 Terminal Complement Complex (TCC)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
E IH |
|
| C5b-9 is also known as the terminal complement complex (TCC). The TCC consists of C5b, C6, C7, C8and C9 and forms the membrane attack complex (MAC) as well as the non-lytic fluid-phase SC5b-9 complex (with protein S). The MAC forms channels in target cell membranes leading to cell lysis by osmotic leakage. The complexes contain neoantigens that are absent from the individual nativecomponents from which they are formed (1,2). | | | Catalog # | C7850-26 | | Applications | Suitable for use in ELISA and Immunohistochemistry. Not suitable for Western Blot. Other applications have not been tested. | | Recommended Dilutions | | | ELISA: 1:20,000 | | Optimal dilutions to be determined by the researcher. | | Culture Medium | RPMI 1640 with 10% fetal calf serum | | Hybridoma | X63.Ag8.653 myeloma cells with spleen cells from Balb/c mice. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG2a/k | | Clone No | 9B1 | | Host | Mouse | | Source | Human | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in PBS, pH 7.4, 0.09% sodium azide. | | Purity | Purified by Protein A affinity chromatography. | | Immunogen | Purified C5b-9. | | Specificity | Recognizes both membrane-bound MAC and fluid-phase of human SC5b-9 complexes. Species crossreativity: porcine adf equine. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | Terminal Complement Complex (TCC) |
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