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You are here:Home » Antibodies » Abs to Complement » Anti -C5b-9 Terminal Complement Complex (TCC) (Biotin)

Anti -C5b-9 Terminal Complement Complex (TCC) (Biotin)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Purified E
C5b-9 is also known as the terminal complement complex (TCC). The TCC consists of C5b, C6, C7, C8 and C9 and forms the membrane attack complex (MAC) as well as the non-lytic fluid-phase SC5b-9 complex (with protein S). The MAC forms channels in target cell membranes leading to cell lysis by osmotic leakage. The complexes contain neoantigens that are absent from the individual native components from which they are formed and is directed against a neoepitope exposed on C9 when incorporated into the TCC.
Catalog #C7850-27B
ApplicationsSuitable for use in ELISA. Other applications not tested.
Recommended DilutionsOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG2a,k
Clone No13A96
HostMouse
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH 7.4, 15mM sodium azide. Labeled with Biotin.
PurityPurified
ImmunogenPurified C5b-9
SpecificityRecognizes human C5b-9. Binds both membrane-bound MAC and fluid-phase SC5b-9 complexes. Species Crossreactivity: porcine, baboon, equine
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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