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You are here:Home » Antibodies » Abs to Complement » Anti -Complement C6 (Complement Component 6, C6)

Anti -Complement C6 (Complement Component 6, C6)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IH
C6, one of the components of the terminal complement complex (TCC), also know as the membrane attack complex (MAC). Proteolytic cleavage of C5 by C5 convertase generates C5b which initiates assembly of the C5b-9 MAC. This complex is assembled from five precursor molecules in the serum, finalized with the polymerization of C9 which accompanies
insertion of the complex into the cell membrane causing cellular lysis. Polymorphonuclear leukocytes represent a major source of C6.
Catalog #C7850-35C
Cellular Localization Secreted
ApplicationsSuitable for use in Western Blot and Immunohistochemistry (Fr). Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
Concentration~0.1mg/ml
FormSupplied as a liquid in PBS, pH 7.2, 1mg/ml BSA, 0.1% sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenNot available.
SpecificityRecognizes C6. Species Crossreactivity: Crossreacts with Mouse. Not yet tested in other species.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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