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Anti -Complement C6 (Complement Component 6, C6)
Anti -Complement C6 (Complement Component 6, C6)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
E IH FC |
|
| Complement component 6 (C6) is a 104kD member of the complement C6/C7/C8/C9 family present in blood serum. The factor I modules of C6 bind the C-terminus of the C5b alpha-chain, anchoring the molecule to the membrane; they also binds complement component 7. This enables the formation of the C5b–7 precursor complex. C5b–7 then functions as a receptor for components C8 and C9 which form the complement membrane attack complex (MAC). Deficiency of C6 results in susceptibility to bacterial infection. | | | Catalog # | C7850-35E | | Applications | Suitable for use in ELISA, Flow Cytometry, and Immunohistochemistry. Other applications not tested. | | Recommended Dilutions | Immunohistochemistry: Frozen sections | | Optimal dilutions to be determined by the researcher. | | Immunohistochemistry Positive Control | Kidney from post streptococcal glomerulonephritis patients | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG1 | | Clone No | 10B400 | | Host | Mouse | | Source | Human | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in Borate buffered saline, 0.1% sodium azide. | | Purity | Purified by Protein A affinity chromatography. | | Immunogen | Purified human Complement C6 | | Specificity | Recognizes human Complement C6. Also recognizes Membrane Attack Comples (MAC). | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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