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Specifications

Clone Host Grade Applications Monoclonal Mouse Affinity Purified E B IH FC

Human C9 is a soluble glycoprotein of 61kD. It is the last component in the assembly of the membrane attack complex (MAC). When the complement is activated on target membranes, multiple copies of C9 bind to the C5b-8 complex and assemble the barrel-shaped pore which causes cell lysis. The conformation of C9 changes from globular to a tubular form. The binding of C9 to C5b-8 plays a key role in the function of C9.
Applications:
Suitable for use in Flow Cytometry, Western Blot, Immunohistochemistry, ELISA, and inhibition of C9 binding to C5b-8. Other applications not tested.
Catalog #	C7850-51A
Recommended Dilutions	Flow Cytometry: 1:10
	Western Blot: 1:10
	Immunohistochemistry (Frozen and paraffin): 1:10
	Optimal dilutions to be determined by the researcher.
Storage and Stability	May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
CAS Number	n/a
Clone Type	Monoclonal
Isotype	IgG1
Clone No	9G176
Host	Mouse
Source	Human
Concentration	~0.1mg/ml
Form	Supplied as a liquid in PBS, 0.1% BSA.
Purity	Purified by Protein G affinity chromatography.
Specificity	Recognizes human Complement C9.
Important Note	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate names	C-term