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You are here:Home » Antibodies » Abs to Complement » Anti -Complement Factor B (C3/C5 Convertase, Glycine-rich beta Glycoprotein, GBG, PBF2, Properdin Factor B, CFB, BF, BFD)

Anti -Complement Factor B (C3/C5 Convertase, Glycine-rich beta Glycoprotein, GBG, PBF2,
Properdin Factor B, CFB, BF, BFD)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E
Complement factor B is a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation.
Catalog #C7850-60J
ApplicationsSuitable for use in ELISA. Other applications not tested.
Recommended DilutionELISA (indirect): 1ug/ml
ELISA (sandwich): 5ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C. For long-term storage, aliquot and store at 4°C. Do not freeze. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG2b
Clone No10K168
HostMouse
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, 0.1% sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenPurified Factor B from human blood.
SpecificityRecognizes human complement Factor B.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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