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You are here:Home » Antibodies » Abs to Complement » Anti -Complement Factor B (C3/C5 Convertase, Glycine-rich beta Glycoprotein, GBG, PBF2, Properdin Factor B, CFB, BF, BFD)

Anti -Complement Factor B (C3/C5 Convertase, Glycine-rich beta Glycoprotein, GBG, PBF2,
Properdin Factor B, CFB, BF, BFD)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Ascites E
Complement factor B is a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation.
Catalog #C7850-60K
ApplicationsSuitable for use in ELISA. Other applications not tested.
Recommended DilutionKT21: 5ug/ml as coating antibody
KT24 peroxidase: 1:1,000 dilution
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C. For long-term storage, aliquot and store at 4°C. Do not freeze. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG2b, IgG1
Clone No10K169
HostMouse
SourceHuman
ConcentrationNot determined
FormKT21
PurityAscites
ImmunogenHuman complement Factor B.
SpecificityRecognizes human complement Factor B Capture/detection antibody pairs: KT21/KT24 peroxidase.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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