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Anti -Complement Factor Bb (Complement Factor B Bb Fragment, Glycine-rich beta Glycoprotein, GBG, PBF2, Properdin Factor B)
Anti -Complement Factor Bb (Complement Factor B Bb Fragment, Glycine-rich beta
Glycoprotein, GBG, PBF2, Properdin Factor B)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
E B FC |
|
| Factor B is present in blood serum. C3b associates with complement factor B, inducing conformational change. This enables complement factor D to cleave the N-terminal of complement factor B (the Ba subunit) leaving the 63kD Bb subunit associated with C3b and forming C3 convertase. Subunit Bb is involved in the proliferation of preactivated B lymphocytes. Conversely, Ba inhibits lymphocyte proliferation. | | | Catalog # | C7850-68 | | Applications | Suitable for use in ELISA, Flow Cytometry and Western Blot. Other applications not tested. | | Recommended Dilution | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG2a | | Clone No | 10B2568 | | Host | Mouse | | Source | Human | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in borate buffered saline, 0.02% sodium azide. | | Purity | Purified by Protein A affinity chromatography. | | Immunogen | Purified human Factor B | | Specificity | Recognizes human Complement Factor Bb. Reacts with a neoantigen of the Bb fragment of human complement factor B. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | Complement Factor B, C3/C5 Convertase, Glycine-rich beta-glycoprotein |
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