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You are here:Home » Antibodies » Abs to Complement » Anti -Complement Factor Bb (Complement Factor B Bb Fragment, Glycine-rich beta Glycoprotein, GBG, PBF2, Properdin Factor B)

Anti -Complement Factor Bb (Complement Factor B Bb Fragment, Glycine-rich beta
Glycoprotein, GBG, PBF2, Properdin Factor B)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B FC
Factor B is present in blood serum. C3b associates with complement factor B, inducing conformational change. This enables complement factor D to cleave the N-terminal of complement factor B (the Ba subunit) leaving the 63kD Bb subunit associated with C3b and forming C3 convertase. Subunit Bb is involved in the proliferation of preactivated B lymphocytes. Conversely, Ba inhibits lymphocyte proliferation.
Catalog #C7850-68
ApplicationsSuitable for use in ELISA, Flow Cytometry and Western Blot. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. 
Clone TypeMonoclonal
IsotypeIgG2a
Clone No10B2568
HostMouse
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in borate buffered saline, 0.02% sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenPurified human Factor B
SpecificityRecognizes human Complement Factor Bb. Reacts with a neoantigen of the Bb fragment of human complement factor B.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesComplement Factor B, C3/C5 Convertase, Glycine-rich beta-glycoprotein


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