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You are here:Home » Antibodies » Abs to Connexin, Junction Proteins » Anti -Connexin 26 (CX26, Gap Junction Beta 2 Protein, CXB-2)

Anti -Connexin 26 (CX26, Gap Junction Beta 2 Protein, CXB-2)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B
Gap junctions were first characterized by electron microscopy as regionally specialized structures on plasma membranes of contacting adherent cells. These structures were shown to consist of cell-to-cell channels. Proteins, called connexins, purified from fractions of enriched gap junctions from different tissues differ. The connexins are designated by their molecular mass. Another system of nomenclature divides gap junction proteins into 2 categories, alpha and beta, according to sequence similarities at the nucleotide and amino acid levels. For example, CX43 (MIM 121014) is designated alpha-1 gap junction protein, whereas CX32 (GJB1; MIM 304040) and CX26 are called beta-1 and beta-2 gap junction proteins, respectively. This nomenclature emphasizes that CX32 and CX26 are more homologous to each other than either of them is to CX43.[supplied by OMIM]
Catalog #C7853-03A
Positive Control Mouse brain lysate
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostGoat
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris-saline, pH7.2, 0.5% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide, YLLIRYCSGKSKKP, representing the C Terminus of the human sequence according to NP_003995.2. Homology
SpecificitySpecies Crossreactivity
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesGJB2, 26kDa (connexin 26), CX26, DFNA3, DFNB1, HID, KID, NSRD1, PPK, Gap junction protein beta 2, CXB-2


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