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You are here:Home » Antibodies » Abs to Connexin, Junction Proteins » Anti -Connexin 26 (CX26, Gap Junction Beta 2 Protein, CXB-2)

Anti -Connexin 26 (CX26, Gap Junction Beta 2 Protein, CXB-2)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B IF
Intercellular communication through gap junctions plays an important role in a variety of cellular processes including homeostasis, morphogenesis, cell differentiation, and growth control. (1-4) Gap junctions are transmembrane channels that serve to directly link neighboring cells by mediating the exchange of low-molecular weight (<1200 D) metabolites, ions, and second messengers. Gap junctions are formed by the interaction of hemichannels (connexons) on adjacent cells. The connexon itself is composed of a hexameric assembly of connexin proteins.
Catalog #C7853-05
ApplicationsSuitable for use in Immunofluorescence, ELISA and Western Blot. Other applications not tested.
Recommended DilutionELISA: 1:500 -1:5000
Immuno uorescence: 1:60-1:250
Western Blot: 1:250-1:1000 Reactivity was confirmed using lysates derived from mouse liver, rat liver and rat brain.
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG2a,k
Clone No3G101
HostMouse
SourceMouse
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS, pH 7.2, 0.1% sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenSynthetic peptide (13aa) corresponding to the C-terminus of mouse Connexin 26. This mouse sequence differs from the rat sequence by a single amino acid and from the human sequence by two (non-consecutive) amino acids.
SpecificityRecognizes mouse Connexin 26. Does not crossreact with Connexin 30. Species Crossreactivity
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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