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You are here:Home » Antibodies » Abs to Connexin, Junction Proteins » Anti -Connexin 30.3 (CX30.3, Gap Junction Beta 5 Protein, CXB5)

Anti -Connexin 30.3 (CX30.3, Gap Junction Beta 5 Protein, CXB5)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IH IF
Connexin 30.3 (Cx30.3) is expressed in the rat kidney, the theca interna and the granulose cell compartment of the porcine ovarian follicle. Mutation of the gene for Cx30. has been tied to Erythrokeratodermia Variabilis (EKV), an autosomal dominant keratinization disorder characterized by migratory erythematous lesions and fixed keratotic plaques. Mutations in Cx30.3 are also involved in hearing impairment.
Catalog #C7853-41
ApplicationsSuitable for use in Immunohistochemistry, Western Blot and Immunofluorescence. Other applications have not been tested.
Recommended DilutionsImmunohistochemistry (Frozen): 2ug/ml
Western Blot: 1-3ug/ml
Immunofluorescence: 2ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceMouse
Concentration~0.25mg/ml
FormSupplied as a liquid in PBS, pH 7.4, 0.1% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to the internal region of the mouse connexin 30.3 protein.
SpecificityRecognizes the ~30kD mouse connexin 30.3 protein. Bands of unknown origins are observed at ~45kD, ~60kD, and between 70-90kD. Reactivity has been confirmed with mouse skin homogenates.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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