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You are here:Home » Antibodies » Abs to Connexin, Junction Proteins » Anti -Connexin 30, GJB6, Gap Junction Protein, beta 6, (30kDa)

Anti -Connexin 30, GJB6, Gap Junction Protein, beta 6, (30kDa)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E
Gap junctions allow the transport of ions and metabolites between the cytoplasm of adjacent cells. They are formed by two hemichannels, made up of six connexin proteins assembled in groups. Each connexin protein has four transmembrane segments, two extracellular loops, a cytoplasmic loop formed between the two inner transmembrane segments, and the N- and C-terminus both being in the cytoplasm. The specificity of the gap junction is determined by which connexin proteins comprise the hemichannel. In the past, connexin protein names were based on their molecular weight, however the new nomenclature uses sequential numbers based on which form (alpha or beta) of the gap junction is present. This gene encodes one of the connexin proteins. Mutations in this gene have been found in some forms of deafness and in some families with hidrotic ectodermal dysplasia.
Catalog #C7853-45
ApplicationsSuitable for use in ELISA. Other applications have not been tested.
Recommended Dilutions
Peptide ELISA Titer: 1:16,000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline, pH 7.2, 0.5% BSA, 0.02% sodium azide.
PurityPurified by peptide affinity chromatography.
ImmunogenSynthetic peptide corresponding to C-RSKRAQTQKNHPNH, from the internal region of human Connexin 30 (NP_006774.2).
SpecificityRecognizes Connexin 30. Species sequence homology
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesgap junction protein, beta 6 (connexin 30), gap junction protein, beta 6, ectodermal dysplasia 2, hidrotic (Clouston syndrome), connexin 30, OTTHUMP00000176872, OTTHUMP00000176871, OTTHUMP00000176870, OTTHUMP00000018096, HED, EDH, ED2, DFNA3, CX30, gap ju


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