Login

Forgot your password?
New User?
Remember me
banner banner

You are here:Home » Antibodies » Abs to Connexin, Junction Proteins » Anti -Connexin 43 (Cx43, Gap Junction Alpha 1 Protein, CxA-1, GJA1, GJAL, Gap junction 43kD heart protein)

Anti -Connexin 43 (Cx43, Gap Junction Alpha 1 Protein, CxA-1, GJA1, GJAL, Gap junction
43kD heart protein)

Pricing

  For pricing information, USA customers sign in.
  Outside USA? Please contact your distributor for pricing.

Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IH
A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexins, through which materials of low molecular weight diffuse from one cell to a neighboring cell. Each connexin is composed of a hexamer of connexin proteins. Connexins are a multi-gene family of highly related proteins. At least a dozen distinct connexin genes have been identified and many are expressed in a tissue-specific manner. Two distinct lineages, class I (beta) and class II (alpha), have been identified in mammals. Connexin-43, also known as Gap Junction Alpha-1 (GJA1), belongs to the class II (alpha) group of connexins and is expressed in the heart and fetal cochlea.
Catalog #C7857-01M
ApplicationsSuitable for use in Immunohistochemistry, Western blot. Other applications have not been tested.
Recommended DilutionsWestern Blot: 0.5-1ug/ml
Immunohistochemistry (formalin fixed and paraffin): 1-2ug/ml. Antigen retrieval is required.
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Dilute in PBS (pH 7.4). Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~1mg/ml after reconstitution
FormSupplied as a lyophilized powder in PBS pH 7.4, 5% BSA, 0.05% Thimerosal, 0.05% sodium azide. Reconstitute in 100ul of sterile ddH2O.
PurityPurified by Immunoaffinity chromatography.
ImmunogenA synthetic peptide corresponding to the amino acids 366-382 from the C-terminus of human Connexin-43.
SpecificityRecognizes Connexin-43. Species crossreactivity: human, mouse, rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


External Links