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Abs to Connexin, Junction Proteins
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Anti -Connexin 43, phosphorylated (Ser368) (Cx43, Gap Junction Alpha 1 Protein, CxA-1)
Anti -Connexin 43, phosphorylated (Ser368) (Cx43, Gap Junction Alpha 1 Protein, CxA-1)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
B |
|
| Connexin 43 (Cx43) is a member of the large family of gap junction proteins. Connexins assemble as a hexamer and are transported to the plasma membrane to create a hemichannel that can associate with hemichannels on nearby cells to create cell-to-cell channels. Clusters of these channels assemble to make gap junctions. Gap-junction communication is important in development and regulation of cell growth. | | | Catalog # | C7857-15 | | Applications | Suitable for use in Western Blot. Other applications not tested. | | Recommended Dilution | Western Blot: 1:1000. Incubate membrane with diluted antibody in TBS, 5% BSA, 0.1% Tween-20 at 4°C with gentle shaking, overnight. | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Host | Rabbit | | Source | Human | | Concentration | As reported | | Form | Supplied as a liquid in 10mM HEPES, pH 7.5, 150 mM sodium chloride, 100ug/ml BSA, 50% glycerol. | | Purity | Purified by immunoffinity chromatography. | | Immunogen | Synthetic phospho-peptide corresponding to residues surrounding Ser368 of human Connexin 43 (KLH-conjugated). | | Specificity | Recognizes Ser368 phosphorylated Connexin 43. Species Crossreactivity: Human, monkey, mouse and rat. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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