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Abs to Connexin, Junction Proteins
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Anti -Connexin 45 (GJC1, Gap Junction protein, gamma 1, 45kD, Cx45, CX45, DKFZp686P0738, Gap junction alpha-7 protein, Gap junction gamma-1 protein, GJA7)
Anti -Connexin 45 (GJC1, Gap Junction protein, gamma 1, 45kD, Cx45, CX45, DKFZp686P0738,
Gap junction alpha-7 protein, Gap junction gamma-1 protein, GJA7)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Sheep |
Serum |
B IF |
|
| Catalog # | C7858-01A | | One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. SUBUNIT | A connexon is composed of a hexamer of connexins. | | Cellular Localization | Membrane; multi-pass membrane protein. Belongs to the connexin family. Alpha-type (group II) subfamily. | | Applications | Suitable for use in Immunofluorescence and Western Blot. Other applications not tested. | | Recommended Dilution | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Host | Sheep | | Source | Human | | Concentration | ~1mg/ml | | Form | Supplied as a lyophilized powder. Reconstitute in 100ul of sterile water. Centrifuge to remove any insoluble material. | | Purity | Serum | | Immunogen | A synthetic peptide (QAYSHQN NPHGPRE) as part of human Connexin-45 protein (aa: 354-367) conjugated to diphtheria toxoid. | | Specificity | Western blotting of cell membarnes of COS cells transiently transfected with cDNA encoding Connexin-45 showsa singular band of molecular weight 47kD which is abolished by preincubation with the immunising peptide. No such band is detected in western blots of membranes from non-transfected cells or cells transfected with cDNA encoding Connexin-37, Connexin-40 or Connexin-45. Species Crossreactivity: This antiserum reacts to human Connexin-45. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | Gap junction alpha-7 protein, Cx45, GJA7 |
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