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You are here:Home » Antibodies » Abs to Connexin, Junction Proteins » Anti -Connexin 50 (Gap Junction alpha-8 Protein, GJA8, Connexin-50, Cx50, Lens Fiber Protein MP70)

Anti -Connexin 50 (Gap Junction alpha-8 Protein, GJA8, Connexin-50, Cx50, Lens Fiber
Protein MP70)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E
GJA8 is a an integral membrane protein that belongs to the connexin family, alpha-type (group II) subfamily. One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. A connexon is composed of a hexamer of connexins. This particular connexin only forms junctional channels. GJA8 is expressed in the eye lens, and defects in GJA8 are the cause of zonular pulverulent cataract type 1 (CZP1), a form of autosomal dominant congenital cataract.
Catalog #C7859-06
ApplicationsSuitable for use in ELISA. Other applications not tested.
Recommended DilutionELISA: 1:4000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to TPSLCPELTTDDAR, from Connexin 50, at the internal region of the protein (NP_005258.2).
SpecificityRecognizes Connexin . Species sequence homology: Bovine, canine, human, mouse and rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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