CBFB, aa1-182, Recombinant, Human (Core-binding Factor Subunit beta, CBF-beta,
Polyomavirus Enhancer-binding Protein 2 beta Subunit, PEBP2-beta, PEA2-beta, SL3-3
Enhancer Factor 1 Subunit beta, SL3/AKV Core-binding Factor beta Subunit)
Pricing
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| CBFB, also known as PEBP2B, is the beta subunit of a heterodimeric core-binding transcription factor belonging to the PEBP2/CBF transcription factor family which master-regulates a host of genes specific to hematopoiesis (e.g., RUNX1) and osteogenesis (e.g., RUNX2). This protein is a non-DNA binding regulatory subunit and it allosterically enhances DNA binding by alpha subunit. | | | Catalog # | C7900-77 | | Source | Recombinant corresponding to aa1-182 of human CBFB protein, fused to His-tag at N-terminus, expressed in E.coli. | | AA Sequence | MGSSHHHHHH SSGLVPRGSH MPRVVPDQRS KFENEEFFRK LSRECEIKYT GFRDRPHEER QARFQNACRD GRSEIAFVAT GTNLSLQFFP ASWQGEQRQT PSREYVDLER EAGKVYLKAP MILNGVCVIW KGWIDLQRLD GMGCLEFDEE RAQQEDALAQ QAFEEARRRT REFEDRDRSH REEMEVRVSQ LLAVTGKKTT RP | | Molecular Weight | 23.6kD (202aa) confirmed by MALDI-TOF | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | Molecular Weight | 23.6kD | | Source | E.coli | | Purity | ~85% (SDS-PAGE). | | Concentration | ~0.5mg/ml | | Form | Supplied as a liquid in 20mM MES, pH 6.0, 0.1mM PMSF, 10% glycerol. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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