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Abs to Transcription Factors, Zinc (Ring) Finger
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Anti -CoREST (REST corepressor 1, Protein CoREST, KIAA0071, RCOR, RCOR1)
Anti -CoREST (REST corepressor 1, Protein CoREST, KIAA0071, RCOR, RCOR1)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
B IP IH |
|
| Brain type II sodium channels are important in neuronal phenotyping and are only seen at high levels in neurons. Studies have shown that CoREST functions as a corepressor for REST. This interaction between REST and CoREST is accomplished by means of a single zinc finger binding motif originating from REST. Together, the REST-CoREST complex mediates long term repression of the type II sodium channel gene (1). | | | Catalog # | C7900-80A | | Applications | Suitable for use in Western Blot, Immunoprecipitation and Immunohistochemistry. Other applications not tested. | | Recommended Dilution | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Host | Rabbit | | Source | Human | | Concentration | ~1mg/ml | | Form | As reported | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | A synthetic peptide that maps to a region between residues 425 and the C-terminus (residue 482) of human REST (RE1-silencing transcription factor) corepressor using the numbering given in entry NP_055971.1 (GeneID 23186). | | Specificity | Species Crossreactivity: Human. Other species have not been tested. Reactivity with mouse CoREST is expected owing to conservation of sequence between this ortholog and human CoREST at the site to which the epitope maps. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | REST corepressor 1, Protein CoREST, KIAA0071, RCOR, RCOR1 |
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