Anti -Coronin 1 (CLABP, CLIPINA, CO1A, CORO1A, Coronin actin binding protein 1A, Coronin
like protein A, Coronin like protein p57, HCORO1, p57, TACO, Tryptophan aspartate
containing coat protein, Clabp TACO, Coronin actin binding protein, 1A, Coronin-1)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
B IP |
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| Coronin 1 was first isolated from Dictyostelium, but similar proteins have been identified in many species and individual cell types. The coronin-like protein in yeast promotes actin polymerization and also interacts with microtubules. Dictyostelium mutants lacking coronin are impaired in cytokinesis and all actin-mediated processes. Analysis of coronin-GFP fusions and knockout mutants shows that coronin participates in the remodelling of the cortical actin cytoskeleton that is responsible for phagocytosis and macropinocytosis. Likewise, in mammalian neutrophils, a coronin-like protein is also associated with the phagocytic apparatus. Coronin 1 binds actin and is found in noninfected macrophages, localised to the cortical microtubule network; in mycobacteria-infected macrophages, progressively relocalized and retained around the mycobacterial phagosomes. | | | Catalog # | C7901-36E | | Applications | Suitable for use in Western Blot and Immunoprecipitation. Other applications not tested. | | Recommended Dilution | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Host | Rabbit | | Source | Human | | Concentration | ~0.2mg/ml | | Form | Supplied as a liquid in TBS, pH 7.2, 0.1% BSA, 0.1% sodium azide. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | The epitope recognized maps to a region between residue 410 and the C-terminus (residue 461) of human Coronin 1 (Coronin, Actin Binding Protein 1A) using the numbering given in entry NP_009005.1 (GeneID 11151). | | Specificity | This antibody is specific to the human Coronin 1 protein. Species Crossreactivity: Human. Other species have not been tested. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | CLABP, CLIPINA, CO1A, CORO1A, Coronin actin binding protein 1A, Coronin like protein A, Coronin like protein p57, HCORO1, p57, TACO, Tryptophan aspartate containing coat protein, Clabp TACO, Coronin actin binding protein, 1A, Coronin-1 |
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Download Specifications for Anti -Coronin 1 (CLABP, CLIPINA, CO1A, CORO1A, Coronin actin binding protein 1A, Coronin like protein A, Coronin like protein p57, HCORO1, p57, TACO, Tryptophan aspartate containing coat protein, Clabp TACO, Coronin actin binding protein, 1A, Coronin-1) |
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