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Specifications

Clone Host Grade Applications Polyclonal Sheep Purified E B IH Gel

Cotinine is an alkaloid found in tobacco and is also a metabolite of nicotine. The word "cotinine" is an anagram of "nicotine". Cotinine has an in vivo half-life of approximately 20 hours, and is typically detectable for several days (up to one week) after the use of tobacco. The level of cotinine in the blood is proportionate to the amount of exposure to tobacco smoke, so it is a valuable indicator of tobacco smoke exposure, including secondary (passive) smoke.[3] People who smoke menthol cigarettes may retain cotinine in the blood for a longer period because menthol can compete with enzymatic metabolism of cotinine.[4] Genetic encoding of liver enzymes may also play a role.) It is used as a biomarker for exposure to tobacco smoke and has also been sold as an antidepressant under the brand name Scotine.
Catalog #	C7904-51B
Applications	Suitable for use in ELISA, Western Blot, Dot Blot, Immunohistochemistry, Immunoassays, development of rapid tests and other antibody recognition assays. Other applications not tested.
Recommended Dilution	ELISA: 2.5ug/ml
	Optimal dilutions to be determined by the researcher.
Storage and Stability	May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
CAS Number	n/a
Clone Type	Polyclonal
Isotype	IgG
Isotype	IgG
Host	Sheep
Concentration	~1mg/ml
Form	Supplied as a liquid in 20mM phosphate, 150mM sodium chloride, pH 7.2, 0.09% sodium azide.
Purity	Purified by ammonium sulfate precipitation.
Immunogen	Cotinine (BTG)
Specificity	Recognizes cotinine.
Important Note	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.