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Abs to Enzymes, Cyclooxygenase (COX)
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Anti -COX 2 (Cyclooxygenase 2, PGHS 2, Prostaglandin Endoperoxide Synthase 2, PHS 2)
Anti -COX 2 (Cyclooxygenase 2, PGHS 2, Prostaglandin Endoperoxide Synthase 2, PHS 2)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Purified |
B IH IC |
|
| Cyclooxygenase catalyzes the first step in the biosynthesis of prostaglandins, thromboxanes, and prostacyclins: the conversion of arachidonic acid to prostaglandin H2. Recent discoveries of the induction of cyclooxygenase biosynthesis by a variety of stimuli such as phorbol esters, lipopolysaccharides, and cytokines led to the hypothesis that the inducible form of cyclooxygenase, COX-2, is responsible for the biosynthesis of prostaglandins under acute inflammatory conditions.10 COX-2 is a 72kDa protein which has been cloned from a variety of species including human, mouse, rat, and sheep. | | | Catalog # | C7904-82F | | Applications | Suitable for use in Western Blot, Immunohistochemistry and Immunocytochemistry. Other applications not tested. | | Recommended Dilution | Western Blot: 0.5ug/ml ( 1:1000) | | Immunohistochemistry: 1:50-1:100 | | Optimal dilution determined by the researcher. | | Storage and Stability | Lyophilized powder may be stored at 4°C for short-term only. Reconstitute to nominal volume by adding sterile 40-50% glycerol and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | Clone Type | Monoclonal | | Isotype | IgG1 | | Clone No | 6D318 | | Host | Mouse | | Source | Human | | Concentration | 0.5mg/ml | | Form | Supplied as a lyophilized powder.Reconstitution: Reconstitute with 100ul sterile, ddH2O or sterile 40-50% glycerol. | | Purity | Purified. | | Immunogen | Synthetic peptide corresponding to aa 580-599 of human COX-2. | | (NASSSRSGLDDINPTVLLKE). | | Specificity | Recognizes human COX-2. Species Crossreactivity: monkey and sheep. Does not crossreact with mouse, rat or rabbit COX-2 or COX-1. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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