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You are here:Home » Antibodies » Abs to Enzymes, Cyclooxygenase (COX) » Anti -COX 2 (Cyclooxygenase 2, PGHS 2, Prostaglandin Endoperoxide Synthase 2, PHS 2) (FITC)

Anti -COX 2 (Cyclooxygenase 2, PGHS 2, Prostaglandin Endoperoxide Synthase 2, PHS 2)
(FITC)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse IC FC
Cyclooxygenase catalyzes the first step in the biosynthesis of prostaglandins, thromboxanes, and prostacyclins: the conversion of arachidonic acid to prostaglandin H2. Recent discoveries of the induction of cyclooxygenase biosynthesis by a variety of stimuli such as phorbol esters, lipopolysaccharides, and cytokines led to the hypothesis that the inducible form of cyclooxygenase, COX-2, is responsible for the biosynthesis of prostaglandins under acute inflammatory conditions. COX-2 is a 72 kDa protein which has been cloned from a variety of species including human, mouse, rat, and sheep.
Catalog #C7904-82K
ApplicationsSuitable for use in Flow Cytometry and Immunocytochemistry. Not recommended for Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionFlow Cytometry: Use 1ug antibody per 10e6 cells
Immunocytochemistry: 2-5ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. FITC conjugates are sensitive to light.
Clone TypeMonoclonal
IsotypeIgG1
Clone No6D319
HostMouse
SourceHuman
Concentration~0.2mg/ml
FormSupplied as a liquid in PBS, pH 7.2, 4mg/ml BSA, 0.02% sodium azide, 50% glycerol. Labeled with fluorescein isothiocyanate (FITC).
PurityPurified
ImmunogenSynthetic peptide corresponding to aa580-599, NASSSRSGLDDINPTVLLKE of human COX-2. Species sequence homology: bovine and canine.
SpecificityRecognizes human COX-2. Species crossreactivity: sheep.
Does not cross-react with mouse, rat, and rabbit COX-2 or COX-1 (all species).
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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