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You are here:Home » Antibodies » Antibodies-Enzymes, Cyclooxygenase (COX) » Anti -COX 2 (Cyclooxygenase 2, PGHS 2, Prostaglandin Endoperoxide Synthase 2, PHS 2)

Anti -COX 2 (Cyclooxygenase 2, PGHS 2, Prostaglandin Endoperoxide Synthase 2, PHS 2)


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Clone Host Grade Applications
Polyclonal Rabbit Purified E B
COX-2 has been cloned from a variety of species including human, rat, and sheep and has a molecular weight of 72kDa.1,2,3,4, COX-2 from these species are approximately 90% identical at the amino acid level, whereas the homology between COX-1 and COX-2 is only about 60%. Expression of COX-2 is regulated by growth factors, tumor promoters, bacterial endotoxin and cytokines, including IL-1 beta.5,6 COX-2 is present in human breast tumors but is not expressed in normal breast tissue.7
Catalog #C7904-82R
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 2ug/ml (1:200)
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
FormSupplied as a liquid in TBS, pH 8.0, containing 50% glycerol and 0.02% sodium azide.
ImmunogenSynthetic peptide corresponding to aa 567-599 (S567VPDPELIKTVTINASSSRSGLDDINPTVLLKE599) of human COX-2.
SpecificityRecognizes human COX-2. Species Crossreactivity: sheep. Does not cross-react with COX-1.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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