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You are here:Home » Antibodies » Abs to Enzymes, Cyclooxygenase (COX) » Anti -COX 2 (PTGS2, prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase), COX2, COX-2, PHS-2, PGG/HS, PGHS-2, hCox-2, prostaglandin G/H synthase and cyclooxygenase)

Anti -COX 2 (PTGS2, prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and
cyclooxygenase), COX2, COX-2, PHS-2, PGG/HS, PGHS-2, hCox-2, prostaglandin G/H synthase
and cyclooxygenase)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Rabbit Supernatant B IC
COX2 (Cyclooxygenase-2. PGHS2) is an inducible dimeric enzyme belonging to prostaglandin G/H synthase family. COX2, similar to COX1, functions to form prostaglandins by catalyzing the synthesis of cyclic endoperoxides from arachidonic acid. COX2 expression is induced by lipopolysaccaride (LPS) and peptoglycan (PGN) and is highly expressed in activated marcophages. It has been implicated as a mediator of inflammation and a possible role in prostanoid signaling in activity-dependent plasticity (1). COX2 is considered as an ideal marker in immune response regulation studies and a therapeutic target against inflammatory diseases (2).
Catalog #C7904-83G
ApplicationsSuitable for use in Immunocytochemistry, Western Blotting. Other applications not tested.
Recommended DilutionWestern Blot: 1:500
ICC: 1:100-250
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Manufactured incorporating RabMAb® technology under Epitomics US patents, No 5,675,063 and 7,429,487, owned by Abcam.
Clone TypeMonoclonal
IsotypeIgG
Clone No9E228
HostRabbit
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid in 50mM Tris-glycine, pH 7.4, 0.15M sodium chloride, 40% glycerol, 0.01% sodium azide, 0.05% BSA.
PuritySupernatant
ImmunogenA synthetic peptide corresponding to residues in human COX-2
SpecificityRecognizes human COX2.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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