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You are here:Home » Antibodies » Abs to Enzymes, Cyclooxygenase (COX) » Anti -COX 2 (PTGS2, Prostaglandin-endoperoxide Synthase 2, Prostaglandin G/H Synthase and Cyclooxygenase, COX2, COX-2, PHS-2, PGG/HS, PGHS-2, hCox-2, Prostaglandin G/H Synthase and Cyclooxygenase)

Anti -COX 2 (PTGS2, Prostaglandin-endoperoxide Synthase 2, Prostaglandin G/H Synthase and
Cyclooxygenase, COX2, COX-2, PHS-2, PGG/HS, PGHS-2, hCox-2, Prostaglandin G/H Synthase and
Cyclooxygenase)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Rabbit Supernatant B IH
COX2 (Cyclooxygenase 2) is an inducible enzyme involved in the response of cells to growth factors, tumor promoters, and cytokines that induce its expression. Given its role in synthesizing prostaglandins, COX2 is of interest in studying immune response regulation. COX2 is induced by a wide variety of stimuli and was initially identified as immediate early growth response gene. In addition, COX2 expression markedly increased in 85-90% of human colorectal adenocarcinoma whereas COX1 levels remain unchanged.
Catalog #C7904-83J
ApplicationsSuitable for use in Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 1:200
Immunohistochemistry (formalin fixed paraffin embedded): 1:100
Optimal dilutions to be determined by the researcher.
Positive ControlLung carcinoma, Colon carcinoma
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG
Clone No11E129
HostRabbit
SourceHuman
ConcentrationNot determined.
FormSupplied as a liquid, 0.05% sodium azide.
PuritySupernatant
ImmunogenSynthetic peptide corresponding to C-terminus of human COX2. Cellular Localization: Cytoplasmic, membrane.
SpecificityRecognizes COX2. Species Crossreactivity: human, mouse and rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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