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You are here:Home » Antibodies » Abs to Enzymes, Cyclooxygenase (COX) » Anti -Cox 2 (Cyclooxygenase-2, Prostaglandin H Synthase)

Anti -Cox 2 (Cyclooxygenase-2, Prostaglandin H Synthase)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Serum E B
COX-2, also known as prostaglandin H synthase, was identified less than a decade ago. Its discovery was followed by a period of discovery and drug development to create a “super aspirin” and led to insights into arthritis, Alzheimer's disease, colorectal cancer and regulation of brain and kidney function in search of better treatments for degenerative and inflammatory diseases. Two different isoforms of the enzyme are known, Cox-1 and Cox-2.
Catalog #C7904-84H
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionELISA: 1:10,000-1:50,000
Western Blot: 1:5000-1:10,000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Freeze at -20°C. Aliquots are stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
HostRabbit
SourceHuman
ConcentrationNot determined.
FormSupplied as liquid in PBS, 0.1% sodium azide.
PurityPurified by delipidation and defibrination.
ImmunogenA GST fusion protein, the epitope of which maps to the carboxy- terminus of human Cox-2.
SpecificityRecognizes Cox-2 at 70kD in Sf9 cell lines transfected with Cox-2 and in WISH cells induced with IL-1b. Does not cross react with Cox-1. Species Crossreactivity: Human, mouse and rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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