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You are here:Home » Antibodies » Antibodies-Prostaglandins » Anti -COX 4-1 (COX IV-1)

Anti -COX 4-1 (COX IV-1)


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Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B
Cytochrome C Oxidase (COX), which is located in the inner mitochondrial membrane, is the terminal enzyme complex of the mitochondrial electron transport chain. It collects electrons that are transferred from reduced Cytochrome C and donates them to molecular oxygen, which is then reduced to water.
Antibodies to this protein make an effective loading control for mitochondria. COXIV (COX4 )is generally expressed at a consistently high level. However, be aware that many proteins run at the same molecular weight as COXIV. Some caution is required when using antibodies to this protein as a loading control, as COXIV expression can vary under some manipulations.
Catalog #C7904-89C
Cellular Localization Mitochondrion, mito inner membrane
Positive Control HEK 293 lysates, Hela lysates
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
FormSupplied as a liquid in Tris-glycine, 150mM sodium chloride, pH 7.2.
PurityPurified by immunoaffinity chromatography.
ImmunogenA synthetic peptide made to an internal region of the human COX41 protein (within residues 1-100). [Swiss-Prot# P13073]. Homology: 100% human, 99% mouse and cow, 92% monkey, 90% rat, and 76% Zebrafish
SpecificityThis antibody is specific for COX41. Species Crossreactivity: This antibody reacts with the human COX41 protein.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesCytochrome C oxidase subunit IV isoform 1, mitochondrial EC=, COX IV-1, Cytochrome C oxidase polypeptide IV, COX4l1, COX4, cox 4-1, COX4-1

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