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You are here:Home » Antibodies » Abs to Protease Inhibitors » Anti -CPI-17 alpha, NT (PKC Potentiated Inhibitor Protein-17)

Anti -CPI-17 alpha, NT (PKC Potentiated Inhibitor Protein-17)


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Clone Host Grade Applications
Monoclonal Rabbit Supernatant B IP IH
PKC Potentiated Inhibitor Protein-17 (CPI-17) is a 17kD protein (1). Expressed in smooth muscles and neuronal cells, CPI-17 is a myosin phosphatase inhibitor protein. Phosphorylation of CPI-17 at Thr38 enhances its inhibitory effect by 100 fold (2). Once phosphorylated, CPI-17 inhibits PP1c and MLCP holoenzyme activity (3).
Catalog #C7905-51
ApplicationsSuitable for use in Western Blot, Immunoprecipitation, Immunohistochemistry. Other applications not tested.
Recommended DilutionWestern Blotting: 1:1,000-5,000
Immunohistochemistry: 1:250-500
Immunoprecipitation: 1:80
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Freeze at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Manufactured incorporating RabMAb® technology under Epitomics US patents, No 5,675,063 and 7,429,487, owned by Abcam.
Clone TypeMonoclonal
Clone No6k132
FormSupplied as a liquid
ImmunogenA synthetic peptide corresponding to residues in the N-term of human CPI-17 aplha
SpecificityRecognizes human CPI-17 aplha
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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