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You are here:Home » Molecular Biology » MB-Protein Kinase Inhibitors » CP-690550, Free Base ((3R,4R)-4-Methyl-3-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-beta-oxo-1-piperidinepropanenitrile, Tasocitinib)

CP-690550, Free Base
panenitrile, Tasocitinib)


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CP-690550 is a novel Janus kinase 3 (JAK3) inhibitor. JAK3 is a critical cytoplasmic tyrosine kinase in the signaling pathways of multiple cytokines (interleukin (IL)-2, -7, -15 and -21) that are associated with various T cell functions. Preclinical and clinical data strongly support that CP-690550, as an immunosuppressant, prevents organ transplant rejection and alleviates the symptoms of autoimmune diseases, such as rheumatoid arthritis (RA) and psoriasis.
Catalog #C7905-90
SolubilitySoluble in DMSO and ethanol at 100mg/ml
Storage and StabilityMay be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
CAS Number477600-75-2
Molecular FormulaC16H20N6O
Molecular Weight312.37
FormSupplied as a white to off-white powder.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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