| The protein encoded by this gene, a member of the carnitine/choline acetyltransferase family, is the rate-controlling enzyme of the long-chain fatty acid beta-oxidation pathway in muscle mitochondria. This enzyme is required for the net transport of long-chain fatty acyl-CoAs from the cytoplasm into the mitochondria. Multiple transcript variants encoding different isoforms have been found for this gene, and read-through transcripts are expressed from the upstream locus that include exons from this gene. |
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| Catalog # | C7906-06B3 |
| Applications | Suitable for use in ELISA and Immunohistochemistry. Other applications have not been tested. |
| Recommended Dilutions | |
| Peptide ELISA Titer: 1:16,000 |
| Immunohistochemistry: 3-5ug/ml; In paraffin embedded Human Heart shows staining of myocardial fibres in longitudinal section. |
| Optimal dilutions to be determined by the researcher. |
| Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. |
| CAS Number | n/a |
| Clone Type | Polyclonal |
| Isotype | IgG |
| Host | Goat |
| Source | Human |
| Concentration | ~0.5mg/ml |
| Form | Supplied as a liquid in Tris saline, pH 7.2, 0.5% BSA, 0.02% sodium azide. |
| Purity | Purified by peptide affinity chromatography. |
| Immunogen | Synthetic peptide corresponding to C-DIADLFQVPKAYS, from the C Terminus of human CPT1B (NP_689452.1; NP_689451.1; NP_004368.1; NP_001138609.1; NP_001138607.1; NP_001138606.1; NP_001138608.1.) |
| Specificity | Recognizes human CPT1B. This antibody is expected to recognise human isoforms a (NP_689452.1; NP_689451.1; NP_004368.1; NP_001138609.1; NP_001138607.1), isoform c (NP_001138606.1) and isoform d (NP_001138608.1). |
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| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
| Alternate names | carnitine palmitoyltransferase I-like, MCPT1, MCCPT1, FLJ58750, FLJ55729, CPT1M, carnitine palmitoyltransferase 1B (muscle), carnitine palmitoyltransferase 1B, carnitine palmitoyltransferase 1A (muscle), carnitine O-palmitoyltransferase I, mitochondrial m |
