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You are here:Home » Antibodies » Abs to Cardiac Markers » Anti -C-Reactive Protein, CT (CRP, MGC88244, PTX 1, PTX1)

Anti -C-Reactive Protein, CT (CRP, MGC88244, PTX 1, PTX1)

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Specifications

Clone Host Grade Applications
Monoclonal Rabbit Affinity Purified B IP IH
Human c-Reactive protein (CRP) was discovered in serum of patients as a nonantibody precipitin of the C-polysaccharide from pneumococci. During acute infection, the amounts of circulating CPR increases 100-1000 fold. Serum CRP values are routinely measured to detect or monitor many human diseases and minor elevations of C-reactive protein are predictive of cardiovascular events in patients with coronary heart disease. CRP promotes host defense, is an efficient activator of the classical C cascade, and shown to be opsonic.The opsonic and C activation activities are responsible for the nonspecific host defense activities providing protection in the preimmune stage of acute infections. Additionally, IL-1 and IL-6 are known to stimulate CRP biosyntesis.
Catalog #C7907-04B
ApplicationsSuitable for use in Western Blot, Immunoprecipitation and Immunohistochemistry. Other applications not tested.
Recommended DilutionsWestern Blot: 1:1000
Immunohistochemistry (Paraffin): 1:100-1:250
Immunoprecipitation: 1:50
Optimal dilutions to be determined by the researcher.
Positive ControlHuman serum and normal human liver tissue
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Manufactured incorporating RabMAb® technology under Epitomics US patents, No 5,675,063 and 7,429,487, owned by Abcam.
Clone TypeMonoclonal
IsotypeIgG
Clone No6k133
HostRabbit
SourceHuman
Concentration~0.1mg/ml
FormSupplied as a liquid in PBS, pH 7.4, 0.05% BSA, 0.01% sodium azide, 50% glycerol
PurityPurified by Protein A affinity chromatography
ImmunogenA synthetic peptide corresponding to residues in the C-terminal of human C-Reactive protein. Cellular Localization: Secreted
SpecificityRecognizes human C-Reactive protein at ~25kD. Does not crossreact with mouse or rat
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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