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Anti -C-Reactive Protein (CRP, MGC88244, PTX 1, PTX1)
Anti -C-Reactive Protein (CRP, MGC88244, PTX 1, PTX1)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Sheep |
Serum |
B |
|
| Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to hosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. COFACTOR: Binds 2 calcium ions per subunit. SUBUNIT: Homopentamer. Pentaxin (or pentraxin) have a discoid arrangement of 5 non-covalently bound subunits. This protein owes its name to its ability precipitate pneumococcal C-polysaccharide in the presence of calcium. Belongs to the pentaxin family. Contains 1 pentaxin domain. | | | Catalog # | C7907-04C | | Cellular Localization | Secreted protein. | | Alternative Products | 2 named isoforms produced by alternative splicing. | | Tissue Specificity | Found in plasma. The concentration of CRP in plasma increases greatly during acute phase response to tissue injury, infection or other inflammatory stimuli. It is induced by IL-1 and IL-6. | | Applications | Suitable for use in Western Blot. Other applications not tested. | | Recommended Dilution | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Host | Sheep | | Source | Human | | Concentration | ~1mg/ml | | Form | Supplied as a lyophilized powder. Reconstitute in 100ul of sterile water. Centrifuge to remove any insoluble material. | | Purity | Serum | | Immunogen | Human recombinant C-Reactive protein. | | Specificity | Specific for C-reactive protein by WB. Species Crossreactivity: Human | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | C reactive protein pentraxin related, CRP, MGC88244, PTX 1, PTX1 |
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