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You are here:Home » Antibodies » Abs to Cardiac Markers » Anti -C-Reactive Protein (CRP, C-Reactive Protein Pentraxin Related, MGC88244, PTX 1, PTX1)

Anti -C-Reactive Protein (CRP, C-Reactive Protein Pentraxin Related, MGC88244, PTX 1,
PTX1)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E
C-Reactive protein (CRP) is an acute phase reactant. CRP is released by the body in response to acute injury, infection, or other inflammatory stimuli. Recent development of a high sensitivity assay for CRP (hs-CRP) has enabled investigation of this marker of systemic inflammation. In addition to binding to phosphocholine residues, CRP can bind to other autologous and extrinsic ligands on targets, including damaged cell membranes, ribonucleoprotein particles, apoptotic cells and constituents of micro-organisms, and may activate the classical complement pathway through C1q recognition, making CRP a factor in a variety of host defense mechanisms. Levels of plasma CRP are significantly increased during the acute phase response, tissue injury and infection and can be used diagnostically as a marker of inflammation, disease progress and risk assessment of cardiovascular disease (CVD).
Catalog #C7907-04K1
ApplicationsSuitable for use in ELISA and Immunodiffusion. Other applications not tested.
Recommended DilutionELISA: 1:1,000-1:15,000
Immunodiffusion: 1:30-1:200
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceHuman
Concentration~5mg/ml
FormSupplied as a liquid in PBS, pH 7.4, 0.09% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenNative
SpecificityRecognizes human C-reactive protein.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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