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Anti -C-Reactive Protein (CRP, MGC88244, PTX 1, PTX1)
Anti -C-Reactive Protein (CRP, MGC88244, PTX 1, PTX1)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Goat |
Serum |
Gel |
|
| C-reactive protein (CRP) is an acute phase reactant. CRP is released by the body in response to acute injury, infection, or other inflammatory stimuli. Recent development of a high sensitivity assay for CRP (hs-CRP) has enabled investigation of this marker of systemic inflammation. | | | Catalog # | C7907-14 | | Atheromatous plaques in diseased arteries typically contain inflammatory cells. Rupture of atheromatous plaque is thought to be the mechanism for acute myocardial infarction and acute coronary syndrome. The most common site of plaque rupture appears to be the shoulder region where inflammatory cells are most prominent. Thus the release of acute phase reactants as a response to inflammation have been proposed as a potential marker of an "unstable" atheromatous plaque and underlying atherosclerosis. | | Studies have shown a positive association between CRP and coronary artery disease. In a survey of 388 British men aged 50-69, the prevalence of coronary artery disease increased 1.5 fold for each doubling of CRP level. Multiple prospective studies have also demonstrated that baseline CRP is a good marker of future cardiovascular events in conjunction with lipid levels. | | Applications | Suitable for use in Turbidmetric, Nephelometric and gel techniques. Other applications not tested. | | Recommended Dilution | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Host | Goat | | Source | Human | | Concentration | ~3mg/ml (Becker) | | Form | Supplied as a liquid in Tris buffer, pH 7.5, 0.1% sodium azide, 40% glycerol. | | Purity | Serum is defibrinated, delipidated and 0.22um sterile-filtered. | | Immunogen | Highly purified (> 99%) human CRP | | Specificity | Monospecific to CRP only (IEP). No reactivity was found against other human proteins. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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