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Anti -C-Reactive Protein (CRP, MGC88244, PTX 1, PTX1)
Anti -C-Reactive Protein (CRP, MGC88244, PTX 1, PTX1)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Goat |
Affinity Purified |
E B |
|
| Pentraxins family of proteins acquired the name from their ability to form pentameric (or decameric) structures formed by non-covalent interactions. C-reactive protein (CRP; mature chain 206aa; chromosome 1q21-23; ~24kD monomer and ~118kD pentamer) is an ubiquitous protein found in both vertebrates and invertebrates. Originally CRP was defined as a substance, observed in the plasma of patients with acute infections that reacted with C polysaccharide of the pneumococcus. It is one of the plasma proteins called acute phase reactants because of a pronounced rise in concentration after tissue injury or inflammation; in the case of CRP the rise may be 1000-fold or more. CRP is composed of 5 identical, 21,500-molecular weight subunits. It is detectable on the surface of about 4% of normal peripheral blood lymphocytes. Acute phase reactant CRP is produced in the liver; those cells produce CRP detectable on lymphocytes. | | | Catalog # | C7907-21G | | Applications | Suitable for use in ELISA and Western Blot. Other applications not tested. | | Recommended Dilution | Western Blot: 1:500-1:5000 | | ELISA: 1:5000-1:20,000 | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Goat | | Source | Human | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in 50mM HEPES, pH 7.1, 0.1M sodium chloride, 0.2% BSA, 0.01% Thimerosal, 40% glycerol. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Purified CRP. | | Specificity | Recognizes human CRP. No reactivity is observed with SAP or other pentraxins. Minimal crossreactivity with rat and mouse CRP. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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