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Anti -C-Reactive Protein (CRP, MGC88244, PTX 1, PTX1)
Anti -C-Reactive Protein (CRP, MGC88244, PTX 1, PTX1)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
E B |
|
| Pentraxins family of proteins acquired the name from their ability to form pentameric (or decameric) structures formed by non-covalent interactions. C-reactive protein (CRP or PTX1; mature chain 206 aa; chromosome 1q21-23) nonglycosylated, ~24kD monomer and ~118kD pentamer) is a ubiquitous protein found in both vertebrates and invertebrates. Originally CRP was defined as a substance, observed in the plasma of patients with acute infections, that reacted with the C polysaccharide of the Pneumococcus. It is one of the plasma proteins that are called acute phase reactants because of a pronounced rise in concentration after tissue injury or inflammation. In the case of CRP the rise may be 1000-fold or more. CRP is composed of 5 identical, 21,500MW subunits. It is detectable on the surface of about 4% of normal peripheral blood lymphocytes. Acute phase reactant CRP is produced in the liver. Those cells produce CRP detectable on lymphocytes. | | | Catalog # | C7907-21L | | Applications | Suitable for use in ELISA and Western Blot. Other applications not tested. | | Recommended Dilution | ELISA: 1:2500-1:10,000 | | Western Blot: 1:250-1:2500 | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Host | Rabbit | | Source | Rat | | Concentration | ~0.5mg/ml | | Form | Supplied as a liquid in PBS, pH 7.4, 0.05% sodium azide before the addition of glycerol to 40%. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Purified rat C-Reactive Protein (CRP). | | Specificity | Specific for rat CRP. No reactivity is observed with SAP or other pentraxins. Species crossreactivity: Minimal crossreactivity with mouse and human CRP. For anti-human CRP, see Cat# C7907-21G. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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