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You are here:Home » Antibodies » Abs to Cardiac Markers » Anti -C-Reactive Protein (CRP, MGC88244, PTX 1, PTX1)

Anti -C-Reactive Protein (CRP, MGC88244, PTX 1, PTX1)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E
C-reactive protein (CRP) is a calcium-binding acute phase reactant belonging to the pentraxin family which is secreted into the plasma by the liver, in response to cytokine stimulation. In addition to binding to phosphocholine residues, CRP can bind to other autologous and extrinsic ligands on targets, including damaged cell membranes, ribonucleoprotein particles, apoptotic cells and constituents of micro-organisms, and may activate the classical complement pathway through C1q recognition, making CRP a factor in a variety of host defense mechanisms. Levels of plasma CRP are significantly increased during the acute phase response, tissue injury and infection and can be used diagnostically as a marker of inflammation, disease progress and risk assessment of cardiovascular disease (CVD).
Catalog #C7907-23
ApplicationsSuitable for use in ELISA and Immunodiffusion. Other applications have not been tested.
Recommended DilutionELISA : 1:1000 -1:15,000
Immunodiffusion: 1:30-1:200
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceHuman
Concentration~5mg/ml
FormSupplied as a liquid in PBS, pH7.4, 0.09% sodium azide.
PurityPurified by affinity chromatography.
ImmunogenPurified native human C-Reactive Protein.
SpecificityRecognizes human C-reactive protein.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesCRP


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