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You are here:Home » Molecular Biology » MB-Cardiac Markers » C-Reactive Protein, Recombinant, Human (CRP, MGC88244, PTX 1, PTX1)

C-Reactive Protein, Recombinant, Human (CRP, MGC88244, PTX 1, PTX1)


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CRP is an acute phase protein that correlates with inflammatory disease and is synthesized by hepatocytes during the acute phase response by certain cytokines (IL-1 and TNF Alpha and Beta). CRP levels increase dramatically (up to 1,000 fold) and serve as a useful marker of inflammation in such conditions as bacterial infection, rheumatoid arthritis, viral infections, transplantation rejection, meningitis, myocardial infarction, septicemia, osteomyelitis and others. CRP is also highly correlated to Serum Amyloid A levels.
Catalog #C7907-28B
Recombinant CRP is a pentamerized active molecule secreted into culture medium during E.coli fermentation with host cells having human CRP gene, allowing r-hCRP to be excreted without cell lysis. The patented technology specifies only active r-hCRP to be manufactured, which is equivalent to native one originated from human tissues. The recombinant CRP is affinity-purified by use of phosphorylcholine conjugated matrices. As a result, the final product presents the longest stability for 2 years as supplied refrigerated.
Applications Standard antigen for CRP determination, rhCRP has been evaluated as a secondary reference material to meet standardization of high sensitive CRP assay. High qualified antigen for antibody production.
SourceHuman, recombinant protein expressed in E. coli
PurityPurified by immunoaffinity chromatography. 96% by SDS-PAGE
FormSupplied as a liquid with buffer.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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