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You are here:Home » Antibodies » Abs to G Protein Receptors » Anti -CRTH2 (Chemoattractant Receptor-homologous Molecule Expressed on Th2 Cells, CD294, CD294 Antigen, DL1R, G Protein-coupled Receptor, GPCR GPR44, GPR44, Putative G Protein Coupled Receptor 44)

Anti -CRTH2 (Chemoattractant Receptor-homologous Molecule Expressed on Th2 Cells, CD294,
CD294 Antigen, DL1R, G Protein-coupled Receptor, GPCR GPR44, GPR44, Putative G Protein
Coupled Receptor 44)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B
CD294 is predominantly expressed on Th2 cells, basophils and eosinophils, and its activation by PDG2 mediates chemotaxis of these cells to inflammatory sites. CD294 may be a useful marker for Th2 cells, and enhances their function and signalling with a possible role in Th2 cell differentiation.
Catalog #C7916-05B
PGD2 is thought to contribute to bronchoconstriction, eosinophilia and mucus production in allergic asthma, and CD294 may contribute to this disease.
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH 7.4, 0.02% sodium azide.
PurityPurified by immunoaffinity chromatography.
Immunogen18 amino acid peptide near the amino terminus of human CD294.
SpecificityRecognizes human CD294. Species Crossreactivity: rat and mouse.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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