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Abs to G Protein Receptors
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Anti -CRTH2 (Chemoattractant Receptor-homologous Molecule Expressed on Th2 Cells, CD294, CD294 Antigen, DL1R, G Protein-coupled Receptor, GPCR GPR44, GPR44, Putative G Protein Coupled Receptor 44)
Anti -CRTH2 (Chemoattractant Receptor-homologous Molecule Expressed on Th2 Cells, CD294, CD294 Antigen, DL1R, G Protein-coupled Receptor, GPCR GPR44, GPR44, Putative G Protein Coupled Receptor 44)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
B |
|
| CD294 is predominantly expressed on Th2 cells, basophils and eosinophils, and its activation by PDG2 mediates chemotaxis of these cells to inflammatory sites. CD294 may be a useful marker for Th2 cells, and enhances their function and signalling with a possible role in Th2 cell differentiation. | | | Catalog # | C7916-05B | | PGD2 is thought to contribute to bronchoconstriction, eosinophilia and mucus production in allergic asthma, and CD294 may contribute to this disease. | | Applications | Suitable for use in Western Blot. Other applications not tested. | | Recommended Dilution | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | 18 amino acid peptide near the amino terminus of human CD294. | | Specificity | Recognizes human CD294. Species Crossreactivity: rat and mouse. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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