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You are here:Home » Antibodies » Abs to Angiogenesis » Anti -CRIM1 (Cysteine-rich Motor Neuron 1 Protein, Cysteine-rich Transmembrane BMP Regulator 1 (Chordin-like), CRIM 1, CRIM-1, Cysteine-rich Repeat-containing Protein S52, MGC138194, Processed Cysteine-rich Motor Neuron 1 Protein, S52) (FITC)

Anti -CRIM1 (Cysteine-rich Motor Neuron 1 Protein, Cysteine-rich Transmembrane BMP
Regulator 1 (Chordin-like), CRIM 1, CRIM-1, Cysteine-rich Repeat-containing Protein S52,
MGC138194, Processed Cysteine-rich Motor Neuron 1 Protein, S52) (FITC)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B IH
Motor neurons are among the earliest neurons to appear after the commencement of cell patterning and the beginning of cell differentiation. Differentiation occurs in a ventral-to-dorsal gradient and is mediated, at least in part, by the concentration of ventrally expressed Sonic hedgehog protein (SHH; MIM 600725). Dorsally expressed factors, such as members of the bone morphogenic protein (e.g., BMP4; MIM 112262) and transforming growth factor-beta (e.g., TGFB1; MIM 190180) families, can repress the induction of these neurons. CRIM1 may interact with growth factors implicated in motor neuron differentiation and survival (Kolle et al., 2000 [PubMed 10642437]).
Catalog #C7921-90-FITC
ApplicationsSuitable for use in ELISA, Immunohistochemistry and Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 1:500-1:1000
Immunohistochemistry (paraffin): 1.5ug/ml
ELISA: 1ug/ml-3ng/ml
Optimal dilutions to be determined by the researcher.
HybridomaSp2/0 myeloma cells with spleen cells from Balb/c mice.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG2a
Clone No10B2602
HostMouse
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2. Contains ~0.09% sodium azide. Conjugated to FITC.
PurityPurified by Protein A affinity chromatography.
ImmunogenRecombinant protein corresponding to a portion of amino acids within aa36-146 of human CRIM1.
SpecificityRecognizes human CRIM1.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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