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Anti -CrkL, phosphorylated (Tyr207) (Crk-like Protein, v-crk sarcoma virus CT10 oncogene homolog (avian)-like)
Anti -CrkL, phosphorylated (Tyr207) (Crk-like Protein, v-crk sarcoma virus CT10 oncogene
homolog (avian)-like)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Rabbit |
Supernatant |
B |
|
| CRKL is a 39kD adaptor protein with one SH2 and two SH3 binding domains. CRKL is the major protein which is tyrosine phosphorylated in response to BCR/ABL (chronic myelogenous leukemia) and growth factor activation. In myeloid cells, it binds to proteins such as paxillin, p130cas and p120 cbl. CRKL aslo appears to bind ABL and SOS. | | | Catalog # | C7925-50D | | Applications | Suitable for use in Western Blot. Other applications not tested. | | Recommended Dilution | Western Blot: 1:2000 | | Optimal dilutions to be determined by the researcher. | | Positive Control | K562 cell lysate | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG | | Clone No | 9H223 | | Host | Rabbit | | Source | Human | | Concentration | As reported | | Form | Supplied as a liquid, 0.05% sodium azide. | | Purity | Supernatant. | | Immunogen | Synthetic peptide surrounding phosporykated tyrosine amino acid 207 of human CRKL. Epitope: Phosphorylated Tyr207 | | Specificity | Recognizes phosphorylated human CRKL. Species sequence homology: mouse and rat (100%). | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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