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C7935-66 Mouse Anti-CRIM1 (Cysteine-rich motor neuron 1 protein)

Specifications
Clone Type
Monoclonal
Host
Mouse
Source
Human
Swiss Prot
Q9NZV1
Isotype
IgG
Clone Number
6E4
Grade
Affinity Purified
Applications
E IHC WB
Crossreactivity
Hu
Shipping Temp
Blue Ice
Storage Temp
-20°C
Cysteine-rich motor neuron 1 protein, cysteine-rich repeat-containing protein S52, GENE NAME: CRIM1

CRIM1 may participate in CNS development by interacting with growth factors involved in motor neuron differentiation and survival. It also has a potential role in capillary formation and maintenance during angiogenesis. It also affects BMP processing and delivery to the cell surface. CRIM1 interacts with BMP4 and BMP7. It localises to the cell membrane and is expressed in a number of tissues including the pancreas, kidney, skeletal muscle, lung, placenta, brain, heart, spleen, liver, small intestine and blood vessels. The unprocessed precursor has a length of 1036 amino acids and a predicted molecular weight of 113.7KDa. CRIM1 contains four antistatin-like domains, one IGFBP N-terminal domain and six VWFC domains. It is also N-glycosylated.

Applications
Suitable for use in Immunohistochemistry, Western Blot and ELISA. Other applications not tested.
Recommended Dilution
Immunohistochemistry: 3ug/ml ELISA: 0.03ng/ml. Optimal dilution determined by the researcher.
Storage and Stability
Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile 40-50% glycerol, ddH2O. Reconstituted product is stable for 12 months at -20°C. Aliquot and store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Immunogen
Partial recombinant human CRIM1 protein (aa36-145) with a GST tag.
Form
Supplied as a lyophilized powder in PBS, pH7.2. Reconstitute with 100ul sterile ddH2O.
Purity
Purified by affinity chromatography.
Specificity
Recognizes human CRIM1.
Conjugates
Pricing
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