Anti -Crystallin AB (Alpha crystallin B chain, CryAB, Alpha (B)-crystallin, Rosenthal
fiber componet, Heat-shock protein beta-5, HspB5, CryA2, AACRYA, Alpha crystallin B chain,
CRYA2, Crystallin alpha polypeptide 2, CTPP 2, CTPP2, Heat shock 20kD like protein,
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
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B |
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| Alpha-crystallin is one of the major structural proteins in the vertebrate eye lenses (2). It occurs as large aggregrates of up to 106 Da composed of two gene products, alphaA-and alphaB-crystallin. These two subunits have a sequence homology of approximately 57%. In humans, the alphaA-crystallin gene encodes a polypeptide of 173 residues and the alphaB-crystallin gene encodes a 175 residue polypeptide. They are related to the small heat proteins (sHspís) (3). The alphaB-crystallin protein, like sHspís, is induced by heat and osmotic shock (4). In addition, alpha-crystallin and sHspís protect other proteins against heat-induced aggregation (6). The two other crystallin families, ß and gama, are homologous to each other but not to the alpha family or the sHspís. | | | | | | Applications: | | | Western Blot (Colorimetric): 1:1,000 | | | Optimal dilutions to be determined by researcher. | | | | | | Positive Controls: | | | Bovine alpha-Crystallin Protein | | | Bovine alphaA-Crystallin Protein | | | Bovine alphaB-Crystallin Protein | | | Catalog # | C7944-60 | | CAS Number | n/a | | Clone Type | Polyclonal | | Host | Rabbit | | Source | Human | | Form | Serum | | Purity | Serum | | Immunogen | Synthetic peptides EEKPTSAPSS and REEKPAVTAAPKK based on the human alphaA crystallin (residues 164-173) and the human alphaB crystallin (residues 163-175) respectively (6), was synthesized and the peptide coupled to KLH. | | Specificity | The antibody Detects a ~20 kD protein, corresponding to the apparent molecular masses of alphaA/alphaB-crystallin on SDS-PAGE immunoblots, in samples from bovine. There is no reactivity with beta-crystallin. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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Download Specifications for Anti -Crystallin AB (Alpha crystallin B chain, CryAB, Alpha (B)-crystallin, Rosenthal fiber componet, Heat-shock protein beta-5, HspB5, CryA2, AACRYA, Alpha crystallin B chain, CRYA2, Crystallin alpha polypeptide 2, CTPP 2, CTPP2, Heat shock 20kD like protein, |
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