Login

Forgot your password?
New User?
Remember me
banner banner

You are here:Home » Antibodies » Abs to Crystallins » Anti -Crystallin AB (Alpha crystallin B chain, CryAB, Alpha (B)-crystallin, Rosenthal fiber componet, Heat-shock protein beta-5, HspB5, CryA2, AACRYA, Alpha crystallin B chain, CRYA2, Crystallin alpha polypeptide 2, CTPP 2, CTPP2, Heat shock 20kD like protein,

Anti -Crystallin AB (Alpha crystallin B chain, CryAB, Alpha (B)-crystallin, Rosenthal
fiber componet, Heat-shock protein beta-5, HspB5, CryA2, AACRYA, Alpha crystallin B chain,
CRYA2, Crystallin alpha polypeptide 2, CTPP 2, CTPP2, Heat shock 20kD like protein,

Pricing

  For pricing information, USA customers sign in.
  Outside USA? Please contact your distributor for pricing.

Specifications

Clone Host Grade Applications
Polyclonal Rabbit B
Alpha-crystallin is one of the major structural proteins in the vertebrate eye lenses (2). It occurs as large aggregrates of up to 106 Da composed of two gene products, alphaA-and alphaB-crystallin. These two subunits have a sequence homology of approximately 57%. In humans, the alphaA-crystallin gene encodes a polypeptide of 173 residues and the alphaB-crystallin gene encodes a 175 residue polypeptide. They are related to the small heat proteins (sHspís) (3). The alphaB-crystallin protein, like sHspís, is induced by heat and osmotic shock (4). In addition, alpha-crystallin and sHspís protect other proteins against heat-induced aggregation (6). The two other crystallin families, ß and gama, are homologous to each other but not to the alpha family or the sHspís.
Applications:
Western Blot (Colorimetric): 1:1,000
Optimal dilutions to be determined by researcher.
Positive Controls:
Bovine alpha-Crystallin Protein
Bovine alphaA-Crystallin Protein
Bovine alphaB-Crystallin Protein
Catalog #C7944-60
Clone TypePolyclonal
HostRabbit
SourceHuman
FormSerum
PuritySerum
ImmunogenSynthetic peptides EEKPTSAPSS and REEKPAVTAAPKK based on the human alphaA crystallin (residues 164-173) and the human alphaB crystallin (residues 163-175) respectively (6), was synthesized and the peptide coupled to KLH.
SpecificityThe antibody Detects a ~20 kD protein, corresponding to the apparent molecular masses of alphaA/alphaB-crystallin on SDS-PAGE immunoblots, in samples from bovine. There is no reactivity with beta-crystallin.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


External Links