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You are here:Home » Molecular Biology » MB-Proteins » CRYGD, Recombinant, Human, aa1-174, His-tag (Gamma-crystallin D, Gamma-D-crystallin, Gamma-crystallin 4, CRYG4)

CRYGD, Recombinant, Human, aa1-174, His-tag (Gamma-crystallin D, Gamma-D-crystallin,
Gamma-crystallin 4, CRYG4)

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Specifications

RYGD belongs to the beta/gamma-crystallin family. Crystallins are the dominant structural components of the vertebrate eye lens. Mammalian lens crystallins are divided into alpha, beta, and gamma families. Gamma-crystallins have been involved in cataract formation. Defects in CRYGD are a cause of cataract autosomal dominant (ADC), cataract congenital non-nuclear polymorphic autosomal dominant (CCP), cataract congenital cerulean type 3 (CCA3) and cataract crystalline aculeiform (CACA).
Catalog #C7944-89
SourceRecombinant corresponding to aa1-174 from human CRYGD, fused to His-tag at N-terminal expressed in E.coli.
AA SequenceMGSSHHHHHH SSGLVPRGSH MGKITLYEDR GFQGRHYECS SDHPNLQPYL SRCNSARVDS GCWMLYEQPN YSGLQYFLRR GDYADHQQWM GLSDSVRSCR LIPHSGSHRI RLYEREDYRG QMIEFTEDCS CLQDRFRFNE IHSLNVLEGS WVLYELSNYR GRQYLLMPGD YRRYQDWGAT
NARVGSLRRV IDFS
Molecular Weight~22.9kD (MALDI-TOF)
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight~22.9kD
SourceE.coli
Purity~95% (SDS-PAGE)
Concentration~1mg/ml
FormSupplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, 5mM DTT, 10% glycerol, 200mM sodium chloride.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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