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You are here:Home » Antibodies » Abs to Signal Transduction » Anti -CSN1 (COP9 signalosome complex subunit 1, COPS1, COP9 constitutive photomorphogenic homolog subunit 1, GPS1, G-Protein Pathway Suppressor 1, MFH protein, Arabidopsis Fus6/Cop11 homol)

Anti -CSN1 (COP9 signalosome complex subunit 1, COPS1, COP9 constitutive photomorphogenic
homolog subunit 1, GPS1, G-Protein Pathway Suppressor 1, MFH protein, Arabidopsis
Fus6/Cop11 homol)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Purified B
COP9 signalosome is a conserved protein composed of eight subunits. Individual subunits of the complex have been linked to various signal transduction pathways leading to gene expression and cell cycle control.
CSN1 is the COP9 subunit 1. The C-terminus of CSN1 is responsible for interacting with CSN2, CSN3, and CSN4 subunits. It is required for incorporation of the subunit into the complex. The N-terminus harbors the activity domain that confers most of the repression functions of CSN1.
Catalog #C7945-50A
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
HostRabbit
SourceHuman
Concentration~1mg/ml
FormAs reported
PurityPurified
ImmunogenA synthetic peptide, representing a portion of human COP9 signalosome complex subunit 1 encoded within exons 13 and 14 (LocusLink ID 2873).
SpecificitySpecific for human CSN1. 100% homology with mouse sequence for immunizing peptide.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesCOP9 signalosome complex subunit 1, COPS1, COP9 constitutive photomorphogenic homolog subunit 1, GPS1, G Protein Pathway Suppressor 1, MFH protein, Arabidopsis Fus6/Cop11 homol


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