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You are here:Home » Antibodies » Abs to Transport Proteins » Anti -CTR1 (copper transporter 1, COPT1, hCTR1, solute carrier family 31 (copper transporters) member 1, SLC31A1)

Anti -CTR1 (copper transporter 1, COPT1, hCTR1, solute carrier family 31 (copper
transporters) member 1, SLC31A1)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IH
The trace metal copper (Cu) plays a crucial role in mammalian cells as a cofactor for many enzymes. Cu-related genetic diseases, such as Menkes disease and Wilson disease, arise from a lack of Cu homeostasis in mammalian cells. CTR1 is a high-affinity copper-uptake protein. The C-terminal domain is similar to the Raf family of protein kinases, but it's first two-thirds encodes a novel protein domain. CTR1 provides the primary avenue for copper uptake in mammalian cells, thereby, affecting Cu homeostasis and embryonic development.
Catalog #C7948-17
Positive Control Human breast cancer and kidney tissue
ApplicationsSuitable for use in Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 1:1000
Immunohistochemistry (paraffin): 1:250
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C. For long-term storage, aliquot and store at 4°C. Do not freeze. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
HostRabbit
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in Tris-citrate/phosphate, pH 7.5, 0.1% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenA synthetic peptide derived from a C-terminal sequence of the human CTR1.
SpecificitySpecies Crossreactivity: This antibody reacts with human CTR1. Other species have not been tested.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namescopper transporter 1, COPT1, hCTR1, solute carrier family 31 (copper transporters) member 1, SLC31A1


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