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Anti -CTR1 (copper transporter 1, COPT1, hCTR1, solute carrier family 31 (copper transporters) member 1, SLC31A1)
Anti -CTR1 (copper transporter 1, COPT1, hCTR1, solute carrier family 31 (copper
transporters) member 1, SLC31A1)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
B IH |
|
| The trace metal copper (Cu) plays a crucial role in mammalian cells as a cofactor for many enzymes. Cu-related genetic diseases, such as Menkes disease and Wilson disease, arise from a lack of Cu homeostasis in mammalian cells. CTR1 is a high-affinity copper-uptake protein. The C-terminal domain is similar to the Raf family of protein kinases, but it's first two-thirds encodes a novel protein domain. CTR1 provides the primary avenue for copper uptake in mammalian cells, thereby, affecting Cu homeostasis and embryonic development. | | | Catalog # | C7948-17 | | Positive Control | Human breast cancer and kidney tissue | | Applications | Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. | | Recommended Dilution | Western Blot: 1:1000 | | Immunohistochemistry (paraffin): 1:250 | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Host | Rabbit | | Source | Human | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in Tris-citrate/phosphate, pH 7.5, 0.1% sodium azide. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | A synthetic peptide derived from a C-terminal sequence of the human CTR1. | | Specificity | Species Crossreactivity: This antibody reacts with human CTR1. Other species have not been tested. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | copper transporter 1, COPT1, hCTR1, solute carrier family 31 (copper transporters) member 1, SLC31A1 |
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